[Immune monitoring and cancer vaccine].

Abstract

NY-ESO-1 antigen is a prototype of a class of cancer/testis antigens. We carried out three serial clinical trials using NY-ESO-1 whole protein, NY-ESO-1f long peptide and overlapping peptides as a cancer vaccine for advanced cancer patients. Although vaccines elicited NY-ESO-1 humoral and cellular immune responses in most patients, results of immune… (More)

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