[Imidazolidine/thiazolidine-acetate aldose reductase inhibitors].

  • P Fresneau
  • Published 2000 in Annales pharmaceutiques francaises


We studied a new family of aldose-reductase inhibitors with an imidazolidine arylmethylene and thiazolidine-acetate structure susceptible to prevent ocular, renal and vascular complications of insulin-dependent diabetes mellitus. We examined the role of the enzyme in the pathological processes involved and reviewed knowledge of known aldose reductase… (More)


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