[Idiosyncratic drug-induced agranulocytosis].

  title={[Idiosyncratic drug-induced agranulocytosis].},
  author={Erik Andres and F Maloisel},
  journal={La Revue de medecine interne},
  volume={27 3},
BACKGROUND Agranulocytosis is a life-threatening disorder that frequently occurs as an adverse reaction to drugs. CURRENT DATA Idiosyncratic drug-induced agranulocytosis is characterized by a neutrophil count <0.5x10(9)/l, in serious forms <0,1x10(9)/l that currently occurs especially in association with antibiotics, antithyroid drugs ant ticlopidine (>60% of the incriminated drugs). The overall incidence of idiosyncratic agranulocytosis ranges from 2.4 to 15.4 cases per million patients… CONTINUE READING