[Hyponatremic coma as a manifestation of Addisońs disease]
@article{Espern2001HyponatremicCA, title={[Hyponatremic coma as a manifestation of Addisońs disease]}, author={Patricia Esper{\'o}n}, journal={Jornal de pediatria}, year={2001}, volume={77 4}, pages={ 337-42 } }
OBJECTIVE: To show the importance of severe hydroelectrolytic disorder as a consequence of previously undiagnosed chronic disease. DESCRIPTION: Case report of hyponatremic coma caused by adrenal crisis in a child with previously undiagnosed Addisońs disease despite suggestive clinical findings of this disease in the last four years. After correction of severe hyponatremia, mild hypovolemia, hypernatriuria and hyperkalemia, the differential diagnosis of this hydroelectrolytic disorder revealed…
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Given multiple GC replacement formulations available comprising short-acting, intermediate, long-acting and novel modified-release hydrocortisone as well as subcutaneous formulations, this review offers a concise summary on the latest therapeutic improvements for treatment of AI and prevention of adrenal crises.
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