[Hypersensitization of alpha-adrenoreceptor of artery smooth muscle in hypertensive rats and hypertensive patients].

Abstract

AIM To investigate the hypersensitization of alpha-adrenoreceptor of artery smooth muscle in hypertensive patients and rats and the mechanisms concerned. METHODS Isometric tension of artery ring segments was recorded by a sensitive myograph system in vitro and the relative amount of alpha-adrenoreceptor mRNA was quantified by a real-time PCR. RESULTS… (More)

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