[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].

@article{Guilland2003HyperhomocysteinemiaAI,
  title={[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].},
  author={J. Guilland and A. Favier and G. Potier de Courcy and P. Galan and S. Hercberg},
  journal={Pathologie-biologie},
  year={2003},
  volume={51 2},
  pages={
          101-10
        }
}
Recent epidemiological studies have suggested that hyperhomocysteinemia is associated with increased risk of vascular disease. Homocysteine is a sulphur-containing amino acid whose metabolism stands at the intersection of two pathways: remethylation to methionine, which requires folate and vitamin B12 (or betaine in an alternative reaction); and transsulfuration to cystathionine which requires vitamin B6. The two pathways are coordinated by S-adenosylmethionine which acts as an allosteric… Expand
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