[How useful is the combination of B vitamins and analgesic agents?].

@article{Jurna1992HowUI,
  title={[How useful is the combination of B vitamins and analgesic agents?].},
  author={Ilmar Jurna and Peter W. Reeh},
  journal={Schmerz},
  year={1992},
  volume={6 3},
  pages={
          224-6
        }
}
Vitamins of the B group have long been used to treat neuropathies of different origins and the accompanying pain. A combination of the vitamins B(1), B(6), and B(12) prevents the slowing of impulse conduction produced by tetanic stimulation in diabetic mice. In patients suffering from diabetic neuropathy, B vitamins alleviate pain in the upper extremities. Thermosensitivity is restored by B vitamins in the upper but not in the lower extremities. It has recently also been reported that a… 
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Vitamin B complex attenuated heat hyperalgesia following infraorbital nerve constriction in rats and reduced capsaicin in vivo and in vitro effects.

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TLDR
This study investigates the extent to which the systemic administration of the vitamins B,, B,, and B,, has an effect on the morphology of a deand regenerating peripheral nerve that has been subjected to cold-induced lesioning.
B-vitamins potentiate the antinociceptive effect of diclofenac in carrageenin-induced hyperalgesia in the rat tail pressure test
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TLDR
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