[High resolution melting analysis for detecting p53 gene mutations in patients with non-small cell lung cancer].


BACKGROUND AND OBJECTIVE It has been proven that p53 gene was related to many human cancers. The mutations in p53 gene play an important role in carcinogensis and mostly happened in exon 5-8. The aim of this study is to establish a high resolution melting (HRM) assay to detect p53 mutations from patients with non-small cell lung cancer (NSCLC), to… (More)
DOI: 10.3779/j.issn.1009-3419.2011.10.01


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