[High glucose increases periostin expression and the related signal pathway in adult rat cardiac fibroblasts].

@article{Zou2010HighGI,
  title={[High glucose increases periostin expression and the related signal pathway in adult rat cardiac fibroblasts].},
  author={Ping Zou and Li-Ling Wu and Dan Wu and D Fan and Xiao-Bing Cui and Yun Zhou and Cheng Wang and Li Li},
  journal={Sheng li xue bao : [Acta physiologica Sinica]},
  year={2010},
  volume={62 3},
  pages={
          247-54
        }
}
Cardiac fibrosis is a major mechanism contributing to myocardial systolic and diastolic dysfunction in diabetic cardiomyopathy. Periostin is a novel extracellular matrix protein, secreted from cardiac fibroblasts, and closely related with cardiac fibrosis and remodeling. The present study aimed to investigate the effect of high glucose on periostin expression and the related signal transduction pathway in cardiac fibroblasts. Adult rat cardiac fibroblasts were cultured and stimulated with high… CONTINUE READING

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