[Heterogeneity of type 1 diabetes mellitus].

  title={[Heterogeneity of type 1 diabetes mellitus].},
  author={S{\'e}rgio Atala Dib},
  journal={Arquivos brasileiros de endocrinologia e metabologia},
  volume={52 2},
Type 1 diabetes (T1D) comprises all forms of autoimmune-mediated and idiopathic beta-cell destruction leading to absolute insulin deficiency. The etiological heterogeneity of T1D has been recognized for the last decades, but it has been divided into only two subtypes so far: autoimmune (T1D)A and non-autoimmune (T1D)B mediated. Polygenic T1DA (isolated or associated to other autoimmune diseases) is the most prevalent type of T1D. T1DA might be part of rare monogenic syndromes related to… CONTINUE READING
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