Corpus ID: 27100637

[Heteroarylalkanoic acids with potential anti-inflammatory activity].

  title={[Heteroarylalkanoic acids with potential anti-inflammatory activity].},
  author={Lina Raffa and Marcella di Bella and Patrizia Ferrari and Agar Monzani and M. G. Andrisano and G. G. Baggio},
  journal={Il Farmaco; edizione scientifica},
  volume={34 3},
A series of (3-oxodihydro-1,2,4-benzothiadiazin-1,1-dioxide-3-yl)acetic acids [compounds of type (A)] and (1,2,4-benzothiadiazin-1,1-dioxide-3-yl)oxyacetic acids [compounds of type (B)] were synthesised and tested for antiinflammatory activity. Preliminary tests showed certain compounds to have a significant level of antiinflammatory activity in rat paw edema induced by carrageenan. It was found that the antiinflammatory activity of this series of compounds depends on the nature, number and… Expand
1 Citations
Synthesis and anti-inflammatory activity of some [2-amino-6-(4-substituted aryl)-4-(4-substituted phenyl)-1,6-dihydropyrimidine-5-yl]-acetic acid derivatives.
Dihydropyrimidines 4a-r have been synthesized by base catalysed condensation of beta-aroylpropanoic acid, guanidine nitrate and aromatic aldehyde and anti-inflammatory activity in vivo was evaluated and compared with standard drug diclofenac sodium. Expand