[Hepatotoxicity of medications].
@article{Barbare2001HepatotoxicityOM, title={[Hepatotoxicity of medications].}, author={Jean-Claude Barbare and Audrey Imbert and Amal Benkirane}, journal={Presse medicale}, year={2001}, volume={30 14}, pages={ 673-6 } }
A TIMELY TOPIC: Liver toxicity remains a common problem despite adequate information for physicians and drug watch programs. The number of recent publications reporting severe drug-induced liver disease emphasizes the need for prudence. ACUTE AND CHRONIC HEPATOTOXICITY: Cases of acute drug-induced liver disease have been described for nearly all drug classes: a few examples concern hepatitis subsequent to administration of fluoxetin, acarbose, riluzole, coumarin, or orlistat. Fulminant…
6 Citations
Liver damage associated with exposure to aspirin and diazinon in male rats and the ameliorative effect of selenium
- Biology, Medicine
- 2014
Adverse reactions and their mechanisms from nimesulide
- Medicine
- 2005
Nimesulide has relatively low occurrences of GI ulcers and bleeding, asthma and respiratory tract reactions and does not appear to have the cardiovascular reactions that has been observed recently with the coxibs and some other NSAIDs.
Early Drug Safety Evaluation: Biomarkers, Signatures, and Fingerprints
- BiologyDrug metabolism reviews
- 2003
Proteomic analysis of the protein profile at the toxic vs. the efficacious dose can provide clues on MOA for the toxicity and may allow differentiation of the pathways of the toxic response from those required for pharmacological activity.
Mechanism of hypolipidemic effect of crocin in rats: crocin inhibits pancreatic lipase.
- Biology, MedicineEuropean journal of pharmacology
- 2006
Saffron against Components of Metabolic Syndrome: Current Status and Prospective.
- BiologyJournal of agricultural and food chemistry
- 2017
This review summarizes the protective role of saffron and its constituents in the pathogenesis of MetS for a better understanding and hence a better management of this disease.