Corpus ID: 11722990

[Hepatoprotective and immunomodulating effect of phylloquinone in toxic damage to the liver].

@article{Konoplia1997HepatoprotectiveAI,
  title={[Hepatoprotective and immunomodulating effect of phylloquinone in toxic damage to the liver].},
  author={E. N. Konoplia and L. Prokopenko and B. S. Uteshev},
  journal={Eksperimental'naia i klinicheskaia farmakologiia},
  year={1997},
  volume={60 3},
  pages={
          75-7
        }
}
  • E. N. Konoplia, L. Prokopenko, B. S. Uteshev
  • Published 1997
  • Medicine
  • Eksperimental'naia i klinicheskaia farmakologiia
  • On entering the organism D-galactosamine (DGA) induces the development of biochemical syndromes of hepatocyte affection, increases the intensity of lipid peroxidation, and suppresses the development of the immune response to the T-dependent antigen. Oral administration of phylloquinone lessens the signs of hepatic damage and increases the immune response to the T-dependent antigen in DGA-induced toxic lesion of the liver. The effects of phylloquinone are mediated by erythrocytes and cytokine… CONTINUE READING