[Hepatocyte oxidant stress and alcoholic liver disease].

@article{Rosa2008HepatocyteOS,
  title={[Hepatocyte oxidant stress and alcoholic liver disease].},
  author={L. Conde de la Rosa and H. Moshage and N. Nieto},
  journal={Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva},
  year={2008},
  volume={100 3},
  pages={
          156-63
        }
}
  • L. Conde de la Rosa, H. Moshage, N. Nieto
  • Published 2008
  • Medicine
  • Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
  • Acute and chronic alcohol consumption increases the production of reactive oxygen species (ROS), and enhances lipid peroxidation of lipids, proteins, and DNA. The mechanism by which alcohol causes cell injury is still not clear but a major role for ROS and lipid peroxidation-end products is considered. Many pathways have been suggested to play a role on how ethanol induces a state of "oxidative stress", including redox-state changes, acetaldehyde production, damage to the mitochondria, membrane… CONTINUE READING

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