[Hepatocyte growth factor (HGF) reduces the expression of profibrotic factors in human isolated glomeruli].

@article{Esposito2003HepatocyteGF,
  title={[Hepatocyte growth factor (HGF) reduces the expression of profibrotic factors in human isolated glomeruli].},
  author={Ciro Esposito and Barbara V. Parilla and Andreana De Mauri and Flavia Cornacchia and Gianluca Fasoli and Annalisa Foschi and Tiziana Mazzullo and Anna Rita Plati and Roberta Scudellaro and Antonio Dal Canton},
  journal={Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia},
  year={2003},
  volume={20 4},
  pages={376-80}
}
BACKGROUND The imbalance between the synthesis and degradation of the mesangial matrix causes glomerulosclerosis and ultimately leads to chronic renal failure. HGF is a pleiotropic cytokine involved in angiogenesis, morphogenesis, organogenesis, and bone remodeling. Recently, we and other investigators have shown that HGF has a central role in the recovery… CONTINUE READING