[Heart failure in women treated with adjuvant trastuzumab for breast cancer].

@article{Tarantini2012HeartFI,
  title={[Heart failure in women treated with adjuvant trastuzumab for breast cancer].},
  author={Luigi Tarantini and Mauro Feola and Adriana Albini and Stefania Gori and Jennifer Foglietta and Maria Antonietta Cicoira and Giovanni Pulignano},
  journal={Giornale italiano di cardiologia},
  year={2012},
  volume={13 5 Suppl 1},
  pages={54S-62S}
}
The amplification of the HER receptor system is present in approximately 20% of breast cancers and confers a marked malignancy and a poor prognosis. Trastuzumab, a monoclonal antibody directed against the HER2 receptor, has dramatically improved the prognosis of patients with HER2+ metastatic and early breast cancer. However, the use of trastuzumab is associated with the possible development of myocardial dysfunction and heart failure. Trastuzumab-induced cardiac injury may be reversible, and a… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…