[HPV16 E6E7 fragments transform immortalized human bronchial epithelial cells into neoplastic cells].

Abstract

OBJECTIVE To study the effects of HPV16 E6E7 fragments on the biological behavior of immortalized human bronchial epithelial cells TR. METHODS E6E7 fragments were constructed into retrovirus expression vector and then transfected into TR cells to observe changes in growth character and tumorigenesis in nude mice. IP-Western blots were done to analyze… (More)

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