[HPLC study of the pharmacokinetics of mezlocillin administered by 30-minute infusion and comparison with the direct intravenous route].

Abstract

Mezlocillin pharmacokinetics were investigated in eighteen patients from a surgical service after a 30 minutes infusion with the purpose, on one hand, to compare this way of administration with a bolus intravenous infusion, and on the other hand to confirm or invalidate capacity-limited dose-dependent pharmacokinetics. Dosages were 2 g (n = 8) and 5 g (n… (More)

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