[HLA-DQ gene and susceptibility of insulin dependent diabetes mellitus in Chinese population].

Abstract

Trans-racial analysis of disease association has improved mapping of MHC-linked susceptibility to insulin dependent diabetes mellitus (IDDM). In this study, the contribution of the HLA class II DQA1 and DQB1 genes was investigated. Nine DQA1 and 10 DQB1 sequence-specific oligonucleotide gene probing in 49 IDDM and 48 control subjects from Beijing showed… (More)

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