[HLA-A29 sub-types and "Birdshot" choroido-retinopathy susceptibility: a possible "resistance motif" in the HLA-A29.1 molecule].

@article{Tabary1991HLAA29SA,
  title={[HLA-A29 sub-types and "Birdshot" choroido-retinopathy susceptibility: a possible "resistance motif" in the HLA-A29.1 molecule].},
  author={Thierry Tabary and Ada Prochnicka-Chalufour and P Cornillet and Phuc Lehoang and Herv{\'e} Betuel and Jacques Henri Max Cohen},
  journal={Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie},
  year={1991},
  volume={313 13},
  pages={599-605}
}
The Birdshot choroidoretinopathy (BSCR) is an ocular disease strongly associated with HLA-A29. The HLA-A29 specificity can be split using immunoelectrofocusing in two subtypes A29.1 and A29.2. BSCR susceptibility is exclusively linked to the HLA-A29.2 molecule. The sequence of HLA-A29.2 was established (EMBL X60108 and found to be identical between patients and healthy individuals. A single difference was found (H----D) 102) in the extra cellular domains between HLA-A29.2 and HLA-A29.1. The HLA… CONTINUE READING