[Growth of experimental neoplasms in mice with inhibition of endogenous prostaglandin synthesis].

Prostaglandin inhibitor--indomethacin was found to significantly suppress the growth of 5 epithelial transplantable tumors in mice. Simultaneously, it stimulated the development of leukemias L-1210 and La and intraperitoneal melanoma B-16. It was also shown to stimulate the spontaneous development of leukemia in mice AKR. Its growth-inhibiting effect was in… CONTINUE READING