[Granuloma formation in mice by liposomes of new glycolipid containing mycolic acids, "trehalose 2,3,6'-trimycolate"].

@article{Yokoi1989GranulomaFI,
  title={[Granuloma formation in mice by liposomes of new glycolipid containing mycolic acids, "trehalose 2,3,6'-trimycolate"].},
  author={F. Yokoi and N. Sugimoto and K. Kato and K. Kaneda and S. Oka and I. Yano},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  year={1989},
  volume={109 1},
  pages={
          46-51
        }
}
  • F. Yokoi, N. Sugimoto, +3 authors I. Yano
  • Published 1989
  • Chemistry, Medicine
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  • After intravenous administration of liposomes containing a novel glycolipid, trehalose 2,3,6'-trimycolate, isolated from Rhodococcus aurantiacus, the granuloma formation was observed distinctively in the lungs, spleen and liver of ICR mice. The concentration of the glycolipid in liposomes influenced profoundly on the inducibility for granulomas and the liposomes containing 10 mol% of trehalose 2,3,6'-trimycolate showed the highest activity for the granuloma formation in mice without a… CONTINUE READING
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