[Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].

@article{Kasper2009GinkgoBE,
  title={[Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].},
  author={Siegfried Kasper and H. Schubert},
  journal={Fortschritte der Neurologie-Psychiatrie},
  year={2009},
  volume={77 9},
  pages={
          494-506
        }
}
The Ginkgo biloba extract EGb 761 interferes with pathomechanisms relevant to dementia, such as Abeta aggregation, mitochondrial dysfunction, insulin resistance, and hypoperfusion. The efficacy of EGb 761 in the treatment of dementia (Alzheimer's disease and vascular dementia) has been studied in 10 randomised, controlled, double-blind clinical trials. In three of the four large trials conducted in accordance with recent recommendations EGb 761 was significantly superior to placebo with respect… Expand
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