[Genetic variation analysis of SARS coronavirus].

  title={[Genetic variation analysis of SARS coronavirus].},
  author={Dongping Xu and Fu-sheng Wang and Ling-xia Zhang},
  journal={Yi chuan xue bao = Acta genetica Sinica},
  volume={31 6},
Severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) has been verified as the causative agent of a worldwide outbreak of SARS. Since the observed per-base replication error-rate of RNA polymerase is about 3 x 10(-5), RNA virus populations typically contain genetic variants that form a heterogeneous virus pool. This feature confers great adaptability on viruses and is partly responsible for current difficulties of viral disease prevention and control, such as of HIV and HCV… CONTINUE READING
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