[Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis].

@article{Kim2004GeneticPO,
  title={[Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis].},
  author={Myong Sik Kim and Don Haeng Lee and Hyo Seung Kang and Hyun Shin Park and Seok Ho Jung and Jin Woo Lee and Kye Sook Kwon and Peter S. Y. Kim and Hyung Gil Kim and Yong Woon Shin and Young Soo Kim and Ilhyun Baek and Myung Seok Lee},
  journal={The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi},
  year={2004},
  volume={43 6},
  pages={
          355-63
        }
}
BACKGROUND/AIMS Susceptibility to organ damage induced by alcohol may be related to inherited variations (polymorphisms) in alcohol-metabolizing enzymes, or polymorphisms affecting cytokines. The aim of this study was to compare the genotype and allelic frequencies of ADH2, ADH3, ALDH2, cytochrome P450-2E1, IL-1, IL-6, IL-8 and tumor necrosis factor-alpha in patients with alcoholic pancreatitis and alcoholic liver cirrhosis with those of controls. METHODS We determined the polymorphism of… CONTINUE READING

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