[Genetic polymorphism of growth hormone gene in adolescent idiopathic scoliosis].

Abstract

OBJECTIVE To investigate whether the growth hormone gene (GH) promotor polymorphism (rs2854184) is associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). METHODS Two hundred and sixty-five AIS patients and 193 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used for… (More)

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