[Genetic polymorphism of growth hormone gene in adolescent idiopathic scoliosis].


OBJECTIVE To investigate whether the growth hormone gene (GH) promotor polymorphism (rs2854184) is associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). METHODS Two hundred and sixty-five AIS patients and 193 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used for… (More)


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