[Genetic and epigenetic changes in colorectal cancer and genetic testing for personalized medicine].

@article{Suehiro2012GeneticAE,
  title={[Genetic and epigenetic changes in colorectal cancer and genetic testing for personalized medicine].},
  author={Yutaka Suehiro and Yuji Hinoda},
  journal={Rinsho byori. The Japanese journal of clinical pathology},
  year={2012},
  volume={60 10},
  pages={976-81}
}
Recent studies have uncovered molecular pathways of colorectal cancer, including the chromosomal instability pathway and microsatellite pathway. In addition, according to genetic and epigenetic profiles, colorectal cancer can be subclassified into 3 distinct groups, named the CpG island methylator phenotype (CIMP) 1, CIMP2, and CIMP negative. CIMP1 is… CONTINUE READING