[Genetic Polymorphisms in Wnt Signaling Pathway and Acute Leukemia].

Abstract

OBJECTIVE To determine the impacts of Wnt signaling pathway products-polymorphisms of rs4135385, rs11079571 and rs7832767 located in β-catenin gene (CTNNB1), Axin gene (AXIN2), and secreted frizzled-related protein gene (SFRP1) on the risk and treatment outcomes of acute leukemia. METHODS Bone marrows (volume 1-1. 5 mL) were collected from 372 untreated… (More)

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