[Gene-environment interaction for the HIF1-A 1772C>T polymorphisms and cigarette smoking increase susceptibility to abdominal aortic aneurysm].

Abstract

Pathological changes in the vascular vessels, such as the presence of atherosclerotic plaques or aneurysmal dilatations, are associated with the local conditions of ischemial/hypoxia. Polymorphisms in the HIF1A gene, encoding an oxygen-regulated HIF-1 subunit (HIF-1a), determine inter-individual variability in vascular response to hypoxia. Stimulation of… (More)

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Cite this paper

@article{Strauss2012GeneenvironmentIF, title={[Gene-environment interaction for the HIF1-A 1772C>T polymorphisms and cigarette smoking increase susceptibility to abdominal aortic aneurysm].}, author={E. J. Strauss and Krzysztof N. Waliszewski and G. Oszkinis and Ryszard Staniszewski}, journal={Przeglad lekarski}, year={2012}, volume={69 10}, pages={744-9} }