[GM3 ganglioside as melanoma specific antigen and its biological function].

@article{Hirabayashi1989GM3GA,
  title={[GM3 ganglioside as melanoma specific antigen and its biological function].},
  author={Yoshio Hirabayashi and Masahiko Taniguchi},
  journal={Human cell},
  year={1989},
  volume={2 1},
  pages={63-9}
}
We have shown that a syngenic monoclonal antibody, M2590, established after immunization of C57BL/6 mice with B16 melanoma cells, recognized GM3 (NeuAc) ganglioside. Although GM3 is widely distributed among various normal cells and tissues, the antibody did not react with them. However, it reacted exclusively with melanoma cells from mouse, hamster and… CONTINUE READING