[Functional analysis of Epstein-Barr virus latent membrane proteins (LMP1) in patients with limphoproliferative disorders].

@article{Smirnova2011FunctionalAO,
  title={[Functional analysis of Epstein-Barr virus latent membrane proteins (LMP1) in patients with limphoproliferative disorders].},
  author={Ksenia Smirnova and Sergey V Diduk and V. {\'E}. Gurtsevich},
  journal={Biomeditsinskaia khimiia},
  year={2011},
  volume={57 1},
  pages={114-26}
}
Latent membrane protein1 (LMP1) encoded by the LMP1 gene of the Epstein-Barr virus (EBV) is a transmembrane protein, which can activate a number of cellular signal cascades and transcriptional factors leading to cell transformation. In the present study the sequencing of full-length LMP1 variants isolated from Russian patients with Hodgkin's lymphoma (HL), non-Hodgkin's lymphomae (NHL) and infectious mononucleosis (IM) has been carried out. The phylogenetic analysis of obtained sequences… CONTINUE READING