[Function of death associated protein kinase(DAPK) in colorectal cancer chemoresistance].

Abstract

OBJECTIVE To investigate the role of death associated protein kinase(DAPK) in colon cancer drug-resistance. METHODS Immunohistochemistry was used to detect DAPK expression in colon carcinoma tissues of 61 cases and adjacent tissues of 32 cases. 5-fluorouracil (5-FU)-induced drug-resistant colon cancer cell lines HCT116/5-FU model was established. DAPK… (More)

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