[Function and toxicity of trace metals in the central nervous system].

Trace metals such as zinc, manganese and iron usually serve the function of metalloproteins in neurons and glial cells, while a portion of trace metals exists in the presynaptic vesicles, and may be released with neurotransmitters. Zinc released into the synaptic cleft may serve as an inhibitory neuromodulator of glutamate release in the hippocampus, while… CONTINUE READING