[Function, molecular structure and gene expression of IL-2 and the receptors].

  • Yasuko Saito
  • Published 1992 in
    Nihon rinsho. Japanese journal of clinical…


The Interleukin 2 receptor is now assumed to be composed of three chains, the L (alpha or Tac), H (beta) chain and p56. The L chain binds IL-2 with low affinity, whereas intermediate-affinity binding of IL-2 is achieved by an association of p56 and the H chain. The high-affinity IL-2R is therefore believed to be a quaternary complex composed of the L chain… (More)


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