[Fcγ receptor and systemic autoimmune disease].

  • Hirofumi Amano
  • Published 2011 in
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese…

Abstract

The systemic autoimmune disease such as systemic lupus erythematosus (SLE) is characterized by the deposition of immune complexes in multiple organs. Fcγ receptors (FcγR) recognize the Fc portion of IgG and are important in determining the response of leukocytes to deposited immune complexes. FcγR also provide positive and negative regulation of immune cell… (More)

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