[Expressions of Cx43 and Skp2 in epithelial ovarian tumor and their clinical significances].

@article{Hu2005ExpressionsOC,
  title={[Expressions of Cx43 and Skp2 in epithelial ovarian tumor and their clinical significances].},
  author={Ye-qing Hu and Yuan-jiao Liu},
  journal={Ai zheng = Aizheng = Chinese journal of cancer},
  year={2005},
  volume={24 1},
  pages={104-9}
}
BACKGROUND & OBJECTIVE Connexin 43 (Cx43), an important member of connexins family, is frequently down-regulated in neoplastic cells. It has been shown to have gap junction-dependent anti-tumor effect on various tumor cell lines. Recently, it was reported that Cx43 could inhibit tumor growth via down-regulating the expression of S-phase kinase associated protein 2 (Skp2). Skp2, a member of F-box protein family, can specifically recognize, and accelerate the ubiquitin-mediated degradation of… CONTINUE READING