[Expression of p38MAPK in the hippocampal CA1 region of rats with Abeta25-35-induced Alzheimer disease].


OBJECTIVE To investigate the changes of p38MAPK expression in a rat model of Alzheimer disease (AD). METHODS Seventy-two adult SD rats were randomized equally into 4 groups, and a single-dose injection of Abeta25-35 (dementia group), normal saline (saline group), SB203580 (inhibitor group), or DMSO (inhibitor control group) was administered into the… (More)