[Expression of matrix metalloproteinases in patients with malignant tumors].

@article{Stancite2004ExpressionOM,
  title={[Expression of matrix metalloproteinases in patients with malignant tumors].},
  author={Diana Stanciūte and Janina Did{\vz}iapetrienė and Jurgis Kadziauskas},
  journal={Medicina},
  year={2004},
  volume={40 12},
  pages={
          1143-50
        }
}
The cancer cells secrete proteolytic enzymes, which are important in the tumor spreading. The cells must cross basement membrane and extracellular matrix barriers in order to spread. The matrix metalloproteinases are a family of endopeptidases, which enzymatic activity depends on the presence of zinc ion in the catalytic domain. Matrix metalloproteinases… CONTINUE READING