[Expression of matrix metalloproteinase-2, -9 and their inhibitor-1 in hypertrophic scars].

OBJECTIVE To investigate the gene expression of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in proliferative and mature hypertrophic scars. METHODS Total RNA from 8 normal skin samples and from 16 human hypertrophic scar samples of different maturing stage was respectively extracted, and then mRNA was… (More)