[Expression of hMLH1 in rectal intraepithelial neoplasm and early rectal carcinoma].

@article{Xuan2012ExpressionOH,
  title={[Expression of hMLH1 in rectal intraepithelial neoplasm and early rectal carcinoma].},
  author={Zhi-xuan Xuan and Guole Lin and Xin-ming Yu and Hui-zhong Qiu},
  journal={Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery},
  year={2012},
  volume={15 11},
  pages={1162-5}
}
OBJECTIVE To explore whether the abnormality of hMLH1 gene may be an early event of carcinogenesis in rectal carcinoma, and to evaluate the diagnostic value in differentiation between intraepithelial neoplasm and early stage of colorectal carcinoma. METHODS The expression of hMLH1 protein in 28 cases with early invasive rectal carcinoma(EIRC), 36 cases with rectal intraepithelial neoplasm(RIEN), and 30 cases with normal rectal mucosa(NRM) which were collected through surgical operations were… CONTINUE READING