[Expression of LRP, MRP and MDR1 in non-small-cell lung cancer and its clinical significance].

@article{Wang2000ExpressionOL,
  title={[Expression of LRP, MRP and MDR1 in non-small-cell lung cancer and its clinical significance].},
  author={Juan Wang and Xiu-ju Liu and Wei-guo Jiang},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={2000},
  volume={22 4},
  pages={304-7}
}
OBJECTIVE To detect expression of lung resistance protein (LRP), multidrug resistance-associated protein(MRP) and multidrug resistance 1(MDR1) mRNA, and its clinical significance in non-small-cell lung cancer (NSCLC). METHODS RT-PCR was used to investigate mRNA expression of the above mentioned genes. RESULTS The frequency of expression of LRP, MRP and MDR1 was 74.2%, 80.3% and 37.9%, respectively. A significant positive correlation was observed between LRP and MRP(r = 0.47, P = 0.001), but… CONTINUE READING