[Expression of CD44 metastatic variant mRNA in colorectal carcinomas and its role in tumor metastasis and invasion].

The expression of CD44 molecules was investigated in colorectal carcinomas by RT-PCR and Southern Blot Analysis. There were significant differences between neoplastic and non-neoplastic colonic mucosa in the expression of CD44 metastatic variant mRNA. The CD44 metastatic variant mRNA was found to be increased in the neoplastic mucosa. However, we could not… CONTINUE READING