[Expression and function of the histamine receptors in dermal and articular tissues].

  • Koichi Ueno
  • Published 2014 in
    Yakugaku zasshi : Journal of the Pharmaceutical…


Histamine was first identified in 1910 as a physiologically active amine. It is now recognized for its multiple regulatory activities in the digestive, neuronal, and immune systems, and new roles are still being elucidated. Histamine exerts its effects through four distinct receptor subtypes. The histamine H4 receptor was identified in 2000 and is the most… (More)


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