[Experimental study on the early liver injury and expression of TNF-alpha mRNA after burns complicated by endotoxemia].

Abstract

OBJECTIVE To observe the distribution and cell localization of TNF-alpha mRNA and its protein and study their role on pathogenesis of liver injury in rats. METHODS An animal model in which rats were subjected to 20% TBSA III degree burns combined with intraperitoneal injection of lipopolysaccharide (LPS) was used for this experiment. The changes in the… (More)

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