[Experimental study on oncogenicity of Aristolochia manshuriensis in rats].

  title={[Experimental study on oncogenicity of Aristolochia manshuriensis in rats].},
  author={Quan-ying Qiu and Zonghui Liu and Helen L. Yin},
  journal={Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine},
  volume={21 4},
OBJECTIVE To observe the oncogenetic process, biological behavior, pathological and immunohistochemical features of tumor induced by Aristolochia manshuriensis (AM) in rats. METHODS Acute renal injury model was established with AM docoction in different dosages by gastrogavage to observe the histomorphologic and immunohistochemical features dynamically. RESULTS (1) At month 0, 1 and 3, the occurrence of renal tumor or tumor-like proliferation was not observed; (2) At month 6, the occurrence… CONTINUE READING