[Experimental studies of the protective effect of deferoxamine mesilate on cisplatin induced toxicity].

@article{Watanabe1998ExperimentalSO,
  title={[Experimental studies of the protective effect of deferoxamine mesilate on cisplatin induced toxicity].},
  author={Hideaki Watanabe and Harumi Kanno},
  journal={Nihon Jibiinkoka Gakkai kaiho},
  year={1998},
  volume={101 8},
  pages={967-78}
}
Cisplatin (CDDP) is an antitumor agent against several types of neoplasms. It has, however, various side effects such as nephrotoxicity and ototoxicity. Several efforts have been made to prevent these toxic side effects. On the other hand, deferoxiamine mesilate (DFO), an iron-chelating agent, has been used for iron-overloaded patients. Since the 1980s… CONTINUE READING