[Experimental epidural and conduction anesthesia with azacaine].
@article{Cherniakova1994ExperimentalEA, title={[Experimental epidural and conduction anesthesia with azacaine].}, author={Iryna Cherniakova and Viktor Nikolaevich Zhukov and S A Osipov and A Sh Shadiev and T V Skovpen'}, journal={Eksperimental'naia i klinicheskaia farmakologiia}, year={1994}, volume={57 1}, pages={ 13-5 } }
Experimental studies were undertaken to examine azacaine used in mice during conduction anesthesia and in rabbits during epidural anesthesia in 0.75, 2 and 0.75, 1% solutions, respectively. It was found that azacaine in the above doses is 1.5-3.5-fold superior to 2% solutions of lidocaine (xycaine) and trimecaine (mesocaine) in their effect duration. Histological studies of the rabbit spinal cord after epidural azacaine administration revealed no significant changes in brain tissues.
2 Citations
Local Anesthetic Activity
- Medicine
- 2015
The mode of action of local anesthetics has been reviewed by Ritchie and Greengard (1966), Ritchie (1971), Borchard (1977), Steiner (1978), and Butterworth and Strichartz (1990).