[Experiences with the rectal use of a chemotherapeutic agent. 1. In vitro biopharmaceutical examinations; selection of the optimal vehicle].

@article{Regdon1998ExperiencesWT,
  title={[Experiences with the rectal use of a chemotherapeutic agent. 1. In vitro biopharmaceutical examinations; selection of the optimal vehicle].},
  author={G{\'e}za Regdon and Istv{\'a}n Er{\"o}s and Z Gombk{\"o}t{\"o} and Jeremy Nemeth and A Vernyik and J{\'a}nos Sallai},
  journal={Acta pharmaceutica Hungarica},
  year={1998},
  volume={68 4},
  pages={224-8}
}
The factors influencing in vitro liberation (Part 1) and in vivo absorption (Part 2) from trimethoprim-containing rectal suppositories and the authors' results related to them are reported in this two-part publication. Special emphasis was laid on selecting the optimal suppository base which is harmless physiologically yet not indifferent pharmacologically… CONTINUE READING