[Evidence of hormone replacement therapy for osteoporosis].

  title={[Evidence of hormone replacement therapy for osteoporosis].},
  author={Ayako Tarakida and Tsuyoshi Higuchi and Hideki Mizunuma},
  journal={Clinical calcium},
  volume={18 10},
Postmenopausal bone estrogen deficiency causes rapid bone loss. Therefore hormone replacement therapy (HRT) has been considered as a rational therapy for postmenopausal not only for osteopenia but also osteoporosis. The results of Women's Health Initiative (WHI) hormone trial had given the strong restriction on HRT. However recent closer analyses have shown that HRT initiated for early menopausal women brings many benefits without elevation of the risks, and that the appropriate selection of… CONTINUE READING


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