• Medicine
  • Published in
    Archives des maladies du…
    1992

[Evaluation of trials on regression of atheromatous lesions with hypolipemic drugs].

@article{Coste1992EvaluationOT,
  title={[Evaluation of trials on regression of atheromatous lesions with hypolipemic drugs].},
  author={Pierre Coste and Claude Durrieu and Pierre Besse},
  journal={Archives des maladies du coeur et des vaisseaux},
  year={1992},
  volume={85 Spec No 2},
  pages={
          189-94
        }
}
Experimental studies have demonstrated regression of atheromatous lesions with diet and lipid lowering drugs. In order to confirm these results clinically, reliable angiographic methods of analysis must be developed along two lines: quantitative by consensus between independent "blinded" experts, qualitative by digitalizing radiological images. Given the reproducibility of these methods, a variation of 17 to 20% in the size of the atheromatous plaques should be required to affirm a change. Five… CONTINUE READING